1·Objective: To observe the effect of Puerari non L-type calcium channel in isolated rat ventricular myocytes.
目的:观察葛根素对大鼠L型钙离子通道的作用。
2·Objective To examine the effect of chloride blockers on volume-sensitive chloride channels in mouse cardiac ventricular myocytes.
目的观察氯通道阻断剂对小鼠心室肌容积敏感性氯通道的影响。
3·Objective To study the electrophysiological characteristics of left ventricular myocytes from spontaneously hypertensive rats (SHR).
目的研究自发性高血压大鼠(SHR)左心室肌细胞的电生理特性。
4·Methods Isolated mouse cardiac ventricular myocytes were subjected to whole-cell patch-clamp to record the hypotonicity activated chloride channel currents.
方法采用急性分离的小鼠心室肌细胞,低渗溶液激活容积敏感性氯通道电流,膜片钳全细胞记录法记录电流。
5·AIM To study the effect of CGRP on L-type calcium channel current in guinea pig ventricular myocytes under normal and imitating ischemia and hypoxia conditions.
目的探讨降钙素基因相关肽(CGRP)对正常及模拟缺血缺氧状态下豚鼠心肌细胞钙通道电流的作用。
6·Objective: To study the membrane ionic basis of action potential prolongation of hypertrophied left ventricular myocytes in spontaneously hypertensive rats (SHR ).
目的:研究自发性高血压大鼠(SHR)左心室肌细胞动作电位时程延长的膜离子流基础。
7·Results: (1) Whole-cell patch-clamp recording technique was established, and highly stable whole cell ion channels' current curves of normal ventricular myocytes were ploted.
结果:(1)建立了膜片钳全细胞记录技术平台,获得了高稳定性的正常心室肌细胞全细胞离子通道电流图。
8·To study the effect of chitosan on delayed outward potassium current(IK) in single ventricular myocytes of guinea pig and investigate its antiarrhythmic mechanism from ion channel view.
研究壳聚糖对豚鼠单一心室肌细胞延迟外向钾电流(I_k)的作用,从离子通道角度初步探讨其作用机理。
9·METHODS: The quasi-steady state current-voltage relationship from the isolated rat ventricular myocytes was measured using whole-cell voltage-clamp techniques with a ramp pulse protocol.
方法:应用全细胞电压箝技术的斜坡脉冲程序,测定离体大鼠心肌细胞准稳态电流-电压关系曲线。
10·Objective To investigate the effect and mechanism of sphingosine 1-phosphate (S1P) on action potential (AP) and voltage-dependent potassium current (KV) in isolated guinea pig ventricular myocytes.
目的研究1 -磷酸鞘氨醇(S1P)对豚鼠心室肌细胞动作电位(AP)及电压依赖性钾电流(KV)的作用及其机制。